Cases of Diphtheria

Diphtheria

Gentlemen,?I have occasionally heard a man, about to read a paper upon some subject, commence by expressing his sense of his unfitness for the task he has undertaken. I have, I must confess, looked upon this appeal, ad misericordiam, with much suspicion, believing the writer, did he not in his own heart believe himself particularly well-fitted for the work, would not have undertaken it. To-day,...

Diphtheria

Investigations of 2 cases of diphtheria-like illness due to toxigenic Corynebacterium ulcerans.

BACKGROUND We present 2 case reports in the United States and investigations of diphtheria-like illness caused by toxigenic Corynebacterium ulcerans. A fatal case occurred in a 75-year-old male Washington resident who was treated with clindamycin but did not receive equine diphtheria antitoxin. A second, nonfatal case occurred in a 66-year-old female Tennessee resident who received erythromycin...

Diphtheria in the Dominican Republic: reduction of cases following a large outbreak.

OBJECTIVE To describe the most recent outbreak of diphtheria in the Dominican Republic and the disease's occurrence and vaccination coverage in 2004-2013. METHODS Clinical data of diphtheria cases that occurred in 2004 and that met the study's case definition were reviewed along with socioeconomic and epidemiological information from the cases' families. Univariate and multivariate analyses w...

OPTIMIZATION OF DIPHTHERIA TOXOID PRECIPITATION BY USING SATURATED AMMONIUM SULPHATE IN ORDER TO IMPROVE DIPHTHERIA VACCINE

سابقه و هدف: کورینه باکتریوم دیفتریه باکتری هوازی و بی­هوازی اختیاری است. مهم­ترین گونه از خانواده کورینه ‌باکتریاها، عامل بیماری دیفتری است که به ­وسیله توکسین خود، بیماری دیفتری را ایجاد می­کند. آمونیم ­سولفات نمکی معدنی است که از آن برای ترسیب و خالص­سازی پروتئین ها استفاده می­شود که با افزایش مقدار نمک حلالیت پروتئینی کم شده و پروتئین ­ها به­ واسطه قطعه­ های هیدروفوب خود، به­هم پیوسته و رسو...